Storing and Carrying Your EpiPen® (epinephrine) Auto-Injector

Filling your EpiPen prescription is an important step in being prepared for a life-threatening allergic reaction (anaphylaxis). Here are some important things to remember:

  • Both EpiPen and EpiPen Jr come in a 2-Pak®. Consider carrying both of your EpiPen Auto-Injectors with you at all times.
  • Always keep your EpiPen Auto-Injector in the carrier tube with the blue safety release on, until you need to use it.
  • Consider keeping EpiPen Auto-Injectors in multiple locations, such as your own home, your purse or bag, a frequently visited friend’s or relative’s home, etc.
  • Pay attention to the expiration date on the side of your EpiPen Auto-Injector and replace it before it expires. You can sign up for a free expiration date reminder right here.
  • Do not store EpiPen Auto-Injector in the refrigerator.
  • Do not store EpiPen Auto-Injector where it may be exposed to extreme cold or heat, such as in your car’s glove box. 

The EpiPen Auto-Injector is not reusable. Even though you might see most of the liquid inside your EpiPen Auto-Injector after use, you have received the right dose and it cannot be used again. You should take your EpiPen Auto-Injector everywhere you go, but it should be kept at room temperature (25°C, 77°F) until the marked expiration date, when it should be replaced.

The effectiveness of this drug may decrease after the expiration date; therefore, care should be taken to promptly refill the prescription before the expiration date. Your EpiPen Auto-Injector should not be refrigerated or exposed to extreme heat or light.

Talk to your health care professional if you need additional EpiPen Auto-Injector 2-Paks to keep at work, school or other locations.

Important Safety Information

EpiPen® (epinephrine) Auto-Injectors contain a single dose of epinephrine, which you inject into your outer thigh. DO NOT INJECT INTO YOUR VEIN, BUTTOCK, FINGERS, TOES, HANDS OR FEET. In case of accidental injection, please seek immediate medical treatment. Epinephrine should be used with caution if you have heart disease or are taking certain medicines that can cause heart-related (cardiac) symptoms.

Tell your doctor if you have certain medical conditions such as asthma, depression, thyroid disease, Parkinson’s disease, diabetes, high blood pressure and heart disease, have any other medical conditions, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. Be sure to also tell your doctor all the medicines you take, especially medicines for asthma. If you have certain medical conditions, or take certain medicines, your condition may get worse or you may have longer lasting side effects when you take the EpiPen or EpiPen Jr Auto Injector.

The most common side effects may include increase in heart rate, stronger or irregular heartbeat, sweating, nausea and vomiting, difficulty breathing, paleness, dizziness, weakness or shakiness, headache, apprehension, nervousness or anxiety. These side effects usually go away quickly, especially if you rest.

Talk to your health care professional to see if EpiPen or EpiPen Jr Auto-Injector is right for you.


EpiPen® (epinephrine) 0.3 mg and EpiPen Jr® (epinephrine) 0.15 mg Auto-Injectors are for the emergency treatment of life-threatening allergic reactions (anaphylaxis) caused by allergens, exercise, or unknown triggers; and for people who are at increased risk for these reactions. EpiPen and EpiPen Jr are intended for immediate self administration as emergency supportive therapy only. Seek immediate emergency medical treatment after use.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit or call 1-800-FDA-1088.

For additional information please contact us at 800-395-3376.