The Role of Epinephrine
Epinephrine is the first-line treatment for life-threatening allergic reactions (anaphylaxis) according to NIH-NIAID food allergy guidelines. It is also the drug product found in the EpiPen® 0.3 mg and EpiPen Jr® 0.15 mg Auto-Injectors. During a life-threatening allergic reaction, epinephrine quickly begins working to treat symptoms of anaphylaxis by constricting blood vessels to increase blood pressure, relaxing smooth muscles in the lungs to reduce wheezing to improve breathing, stimulating the heart (increasing heart rate) and working to reduce hives as well as swelling that may occur around the face and lips.
If you, your child or someone you’re caring for is experiencing a life-threatening allergic reaction, use the EpiPen or EpiPen Jr Auto-Injector promptly and seek emergency medical attention.
Be sure to tell your doctor all the medicines you take, especially medicines for asthma. Side effects may be increased in patients with certain medical conditions or who take certain medicines. These include asthma, allergies, depression, thyroid disease, Parkinson's disease, diabetes, high blood pressure and heart disease.